Need To Know
No, cannabis is federally prohibited under the Controlled Substances Act. Currently, there are no federal rules related to cannabis testing due to the plant’s Schedule 1 status. Cannabis is legal state to state and testing regulations vary depending on the state. USDA testing guidelines only exist for hemp, which is legal as long as it contains less than 0.3% Delta-9 THC by dry weight.
The federal government designates psilocybin and psilocin as Schedule 1 controlled substances; therefore, there are no federal regulations designed for magic mushroom testing. However, the DEA does allow companies to apply for federal psilocybin registration. Under this designation, a company can conduct any of seven activities, including manufacturing, distribution, reverse distribution, research, import, export, and chemical analyses. DEA license holders may be required to conduct testing if they are involved in chemical analysis or research .
CBN is very similar to CBD in its chemical structure and therapeutic profile. Still, it has essential distinctions in how it occurs and its potential for mild psychoactive effects.
- CBN primarily forms as THC ages, resulting in mild psychoactive effects, unlike CBD, which is non-psychoactive.
- CBN binds weakly to CB1 receptors, contributing to its sedative properties and making it potentially useful for sleep disorders. CBD does not bind with CB1 receptors.
Both cannabinoids show anti-inflammatory and analgesic effects, but CBN has unique antibacterial properties and may stimulate appetite. CBD, on the other hand, is more widely researched for anxiety, epilepsy, and neuroprotection, highlighting its broader therapeutic potential.
Yes, in order to grow, process, distribute, and sell Medical Cannabis in the state of Florida, you must be licensed by the Office of Medical Marijuana Use (OMMU) as a Medical Marijuana Treatment Center (MMTC). Hemp growers, processors, and distributors must also apply for a permit within their State, and growers must apply with the USDA directly if the State does not have a hemp permit program. OR: if only talking about Florida: Hemp growers, processors, and distributors in Florida, must apply for a permit with the FL Department of Agriculture. As of June 16th, the manufacturer’s permit number must also be listed on the COA in states like Florida.
Yes, to grow psychedelic mushrooms in the United States, the DEA must approve the company for federal psilocybin regulation, or the company must be in a state with a regulatory agency set up to govern the use of mushrooms, such as Oregon. However, cultivators do not typically need a license to grow functional mushrooms.
Yes. Licensees must complete cannabis laboratory testing to comply with their state’s health department or governing body. In Florida, that regulatory body is the Office of Medical Marijuana Use, and it operates under the Florida Department of Health. ACS Laboratory offers Florida Medical Marijuana Treatment Center (MMTC) compliance panels, along with la carte R&D testing services, to help companies develop premium-quality medical cannabis products.
Mushroom testing requirements depend on the species and the state of sales. Psilocybin mushroom licensees in Oregon and Colorado must conduct mushroom testing to prove they comply with the state’s rules. Functional mushroom producers selling ingestible products in the U.S. are generally not required to conduct state or federal lab testing. However, they are responsible for ensuring safety and quality. Many producers choose third-party testing to verify the potency and purity of active compounds, especially for popular varieties like Lion’s Mane, Reishi, and Cordyceps. Amanita muscaria producers are also not required by federal or state law to conduct lab testing for quality or potency, as this mushroom occupies a regulatory gray area. However, top-tier brands submit Amanita samples to ACS Laboratory to determine precise potency and rule out the presence of contaminants.
The Amanita muscaria species does not contain psilocybin or psilocin. Rather, the active chemicals in this mushroom are muscimol, ibotenic acid, and muscarine.
Yes. Smoking THCA via smokeable flower or vapes provides sufficient heat to convert a significant portion of the compound into regular THC. Yes, THCA (tetrahydrocannabinolic acid) transforms into THC (tetrahydrocannabinol) when smoked. This transformation occurs through a process known as decarboxylation, which is initiated by heat. When THCA is exposed to high temperatures, such as those produced by smoking or vaping, it loses a carboxyl group and converts into THC, which is the psychoactive compound responsible for the "high" associated with cannabis use 1. The conversion is efficient; for instance, when smoking THCA flowers, a significant percentage of the THCA can convert to THC, allowing users to experience its psychoactive effects 2. This means that while THCA itself does not produce a high, once it is heated, it becomes THC, which does have psychoactive properties.
White Maeng Da, one of the most potent kratom strains, can only be detected in tests specifically designed to identify the plant's‚ alkaloids (mitragynine and 7-hydroxymitragynine). It is not detectable in routine drug screenings.
Kratom is not detected in standard 5-panel drug tests. However, some employers and organizations use more comprehensive drug testing panels that can identify kratom compounds.
ACS uses incredibly accurate high-performance liquid chromatography (HPLC) equipment during cannabis potency testing, which measures cannabinoids, flavonoids, and terpenes. This method detects compounds to 1/10th of 1% and 1/10th of a milligram, measured in parts per billion.
ACS Laboratory’s Amanita potency and psilocybin potency tests, which measure active compounds and amino acids using Liquid Chromatography Mass Spectrometry, are highly accurate. They can even quantify trace substances to 1/10th of 1% and 1/10th of milligrams, measured in parts per billion.
Cannabis products are tested through a number of quantitative testing measures and analytical instruments, including HPLC/UV, GC/MS, and ICP/MS.
Mushroom products are tested through a number of quantitative testing measures and analytical instruments, including HPLC/MSMS/HPLCUV, GC/MS, and ICP/MS.
Use the Certificate of Analysis (COA) provided by ACS Laboratory to create accurate labels using lab testing data. The COA includes detailed results on potency, contaminants, and other key metrics, which you can use to populate label information accurately. ACS provides a unique QR code linked to every COA that you can print on your product packaging, enabling consumers to scan it for full transparency.
Labeling is the final piece of the puzzle. As stated above, unique QR codes are provided with each and every report to enable full transparency.
ACS Laboratory publishes test results with a lab report known as a certificate of analysis (COA). This easy-to-read, verified document linked via a QR code details the results of all panels, including potency and contaminant screenings for heavy metals, pesticides, molds, and bacteria. You can access your COAs through the Mahi portal, a digital platform provided by ACS Laboratory, which securely stores data and allows you to review and download results anytime. For help interpreting your COA, visit the Mahi portal, review our How to Read a COA guide, or contact your customer success agent, who can walk you through the results and answer any questions.
Please click the “Start Testing” button or fill out the form on our website and one of our account specialists will reach out to you ASAP to get you any and all information and forms needed to set up an account with ACS Laboratory and submit samples to us.
Most people use White Maeng Da in low to moderate doses for an energy boost and enhanced focus. Beginners often start with 1-2 grams to assess tolerance and minimize side effects. Health experts advise consulting a doctor, especially for people with pre-existing health conditions.
Processing methods like drying, fermentation, and blending alter kratom’s alkaloid profile, which affects its potency and effects. For example, extended sun drying creates white kratom with energizing effects, while fermentation produces red kratom with relaxing properties. These processes give each strain its unique characteristics.
ACS uses various quantitative mushroom testing measures and analytical instruments, including high-performance liquid chromatography (HPLC) with UV detection (HPLC/UV) and electrospray ionization tandem mass spectrometry (MS/MS) for potency, gas chromatography/mass spectrometry (GC/MS) to detect contaminants like solvents and pesticides, and inductively coupled plasma mass spectrometry (ICP/MS) for detecting heavy metals.
ACS Laboratory simplifies its kratom test results by setting clear pass/fail parameters for heavy metals and microbial contaminants, following American Herbal Products Association (AHPA) guidelines. This straightforward approach allows clients to assess product safety quickly without technical expertise. Clear indicators make it easy for consumers to see that their products meet essential quality standards.
ACS Laboratory uses advanced testing methods to detect six heavy metals in kratom products: arsenic, cadmium, lead, mercury, nickel, and manganese. These tests meet stringent safety standards to protect consumers from contamination risks.
ACS Laboratory uses Liquid Chromatography Mass Spectrometry (LCMS) to measure kratom’s alkaloid levels precisely. This method quantifies active ingredients to 1/10th of 1% and detects even trace amounts in parts per billion. Such accuracy gives consumers and brands a reliable profile of each product’s potency.
ACS tests cannabis and hemp products using various quantitative testing measures and analytical instruments, including high-performance liquid chromatography with ultraviolet detection (HPLC/UV), gas chromatography/mass spectrometry (GC/MS) to detect contaminants like solvents and pesticides, and inductively coupled plasma mass spectrometry (ICP/MS) for cannabis heavy metals testing. ACS also uses Liquid Chromatography and Mass Spectrometry (LCMS) to test for the potency of cannabinoids to the billionth decimal point!
CBC and CBD are both non-psychoactive cannabinoids found in the cannabis plant, each with unique properties and potential therapeutic benefits. CBC interacts primarily with the TRPV1 and TRPA1 receptors, which affect pain perception and inflammation. In contrast, CBD interacts with several receptor systems, including the 5-HT1A serotonin receptor, which contributes to its anxiolytic (anxiety-reducing) effects, and the GPR55 receptor, which may regulate blood pressure and bone density. CBD is well-known for its anti-inflammatory, analgesic, and antiepileptic properties.
CBDVA has an extra carboxyl group, which makes it less bioactive in its raw form than CBDV. Conversely, CBDV is the active form, allowing it to interact more readily with the endocannabinoid system. That said, neither compound significantly affects the ECS. Both are non-psychoactive and may exhibit similar therapeutic potential through their anti-inflammatory properties. However, CBDVA research is scant and limited to preclinical studies.
THCA does not bind to neural cannabinoid receptors with nearly the same strength as THC. However, THCA impacts other channels that help prevent neurodegeneration and promote brain health. This mechanism could supplement treatment for conditions such as Alzheimer's, Parkinson's, and Huntington's.
CBD (cannabidiol) and THCA are major cannabinoids found in cannabis and hemp plants with similar benefits. Both are highly anti-inflammatory and may benefit people with seizure disorders. However, CBD is more known for its anxiety-relieving properties, while THCA may offer stronger neuroprotection. THCA and CBD are also both non-psychoactive. However, THCA transforms into regular THC when heat is applied through smoking or cooking. That means THCA has powerful psychoactive potential, while CBD is always non-psychoactive. Both THCA and CBD have different chemical structures, which contribute to their unique effects and interactions with the body’s endocannabinoid system. THCA is the acidic precursor to THC, while CBD is a distinct compound that interacts differently with cannabinoid receptors.
White Maeng Da provides a more stimulating effect than red or green strains. Red strains are typically sedative, while green offers a balanced effect. Many fans choose it over others when seeking an energizing, mood-boosting experience.
Body weight affects a person’s metabolism and tolerance level. Generally, people with higher body weight may require larger Amanita doses to achieve the same effects as those with lower body weight. This variation occurs because a larger body mass can dilute the concentration of the substance.
Mitragynine and related active compounds in kratom, like 7-OH-mitragynine, bind to the body’s opioid receptors distributed mainly throughout the central nervous system. This interaction can cause sedation or stimulation (depending on the dose), pleasure, and pain relief.
The KCPA sets quality standards for kratom products, including testing requirements for purity, potency, and safety. Testing through ACS Laboratory helps brands meet these legal standards, boosting consumer trust and ensuring compliance with state regulations. Adhering to these standards also strengthens the kratom industry’s reputation for safety.
7-hydroxymitragynine is like morphine in that it acts as an opioid receptor agonist, explicitly targeting the mu-opioid receptors in the brain. Both substances can produce analgesic (pain-relieving) effects and may induce euphoria or sedation. However, 7-hydroxymitragynine is structurally different and is derived from the kratom plant, whereas morphine is a naturally occurring opiate derived from the opium poppy plant. Additionally, 7-hydroxymitragynine is generally considered to be more potent than morphine in terms of its effects on opioid receptors, although potentially less addictive when consumed in whole-plant form.
ACS Laboratory provides a 5 day turnaround time for kratom test results.
Cannabis and hemp testing typically require 1—to 17-gram sample sizes, depending on the panel and product type. You can view a sampling requirements chart here, with a separate chart for Colorado clients. Mushroom and kratom brands can fill out the contact form or call 561-510-8396 to receive information about sample size and submission. In fact everyone can do that, just to make sure they are getting their questions answered.
ACS Laboratory customizes testing pricing based on your objectives and volume. Please either visit our “Start Testing” tab on the website, email info@acslab.com, or call 561-510-8396 for quotes.
ACS Laboratory recommends testing hemp crops every week after the flowering phase for each plant variety to ensure they test below the 0.3% THC limit.From a compliance perspective, FL state regulations require that hemp flower be sampled for compliance by the certified laboratory 15-30 days before harvest. Cultivators must submit a Notice of Harvest to the Department at least 30 days prior to the intended harvest date, per Rule 5B-57.014. And schedule sample collection for compliance testing about 15 to 30 days before harvest. In addition to testing THC potency for compliance, ACS Laboratory offers various R&D hemp testing options in the pre-harvest phase that ensure healthy growth and development. These include pre-planting soil and elemental analysis, micronutrient testing to pinpoint mineral deficiencies, and measuring THCA , Delta 9, and CBDA, which contribute significantly to total THC and CBD levels in final products.
After submitting your first samples to ACS Laboratory, expect to receive results via email within three to five business days of sample receipt. Each product’s results come with a Certificate of Analysis (COA) in PDF form, which includes detailed testing results on potency and contaminants. For greater accessibility, ACS Laboratory also stores these COAs in the Mahi portal, a secure online platform where you can view and download COAs anytime. Each COA is linked to a unique QR code that you can display on product labels or websites. This enables customers to scan and instantly access test details and critical results.
No problem. You can get your cannabis, hemp, mushroom, or kratom samples to our lab through various submission methods. Florida Medical Marijuana Treatment Centers (MMTCs) must sign a chain of custody form, allowing ACS to have a courier driver service to pick up samples at the MMTC location. Hemp, CBD, functional mushroom, kratom, and Amanita muscaria clients from across the U.S. can send samples via USPS, FedEx, or UPS directly to the laboratory just south of Tampa, Florida. Clients must Register and submit Order forms to initiate the process. Contact ACS to get started, International hemp, mushroom, and kratom brands can contact ACS about the process for mailing samples to the lab. Lab Address:ACS Laboratory721 Cortaro DriveSun City Center, FL 33573
Kratom is federally legal in the U.S. However, some states have banned or restricted kratom sales and use. Alabama, Arkansas, Indiana, Rhode Island, Vermont, and Wisconsin prohibit kratom entirely. At the same time, other states, like Florida, Georgia, and Arizona, have passed the Kratom Consumer Protection Act (KCPA) to regulate its safety and quality. Consumers must check local regulations to understand the legal status of Kratom in your area.
Mitragynine is not stronger than morphine. However, some of its derivatives and related alkaloids have shown higher potency than morphine in animal studies. For instance, one study found that mitragynine pseudoindoxyl was three times more potent than morphine in mice, and 7-hydroxymitragynine was 5-fold more potent. Another study reported that 7-hydroxymitragynine exhibited 13- and 46-fold higher potency than morphine and mitragynine.
Muscimol is a potent and selective orthosteric agonist for the GABA receptors. This mechanism means it displays sedative-hypnotic, depressant, and hallucinogenic psychoactivity at high doses. However, it is not a classic psychedelic. It is regarded as a deliriant.
There are no recorded instances of muscimol dependence. Most agree muscimol is well tolerated and non-habit-forming, even in larger, psychoactive doses. However, muscimol misuse is theoretically possible, as is true with all chemical substances, such as those in McDonald's french fries.
Cannabis and muscimol are both psychoactive substances that can make people feel happy and relaxed. However, they elicit fairly distinct effects. Muscimol delivers dream-like, sedative effects, while THC provides a more euphoric and sensory-enhancing high.
ACS Laboratory’s Amanita Testing includes potency testing of Ibotenic Acid, Muscarine, and Muscimol, as well as purity analyses for pesticides, mycotoxins, residual solvents used when making extracts or edibles, heavy metals, microbiological compounds, and water activity and moisture.
ACS tests for eight kratom alkaloids: mitragynine, paynantheine, speciogynine, Speciociliatine, 7-OH-mitragynine, mitraphylline, Isorhynchophylline, and corynoxine. This analysis helps to determine the product’s effects and therapeutic profile.
Functional Mushrooms can be tested for Pesticides (FL -list and action levels), Mycotoxins (FL list and action levels), Residual Solvents for Extracts (FL list and action levels), Heavy metals (FL list and action levels), Microbiological (FL Compliance 1), Water activity and moisture (useable)What kind of mushroom products can you test?We analyze and test a variety of common mushrooms, finished products, and delivery vehicles, including dried, chocolates, tinctures, gummies, and capsules.
Psychedelic Mushrooms are tested for the potency of Psilocybin, Psilocin ,Harmine, Harmane, Baeocystin, Norbaeocystin, Norpsilocin, Aeruginascin, 4-hydroxy TMT. They can also be tested for 1. Pesticides (FL -list and action levels) 2. Mycotoxins (FL list and action levels) 3. Residual Solvents for Extracts (FL list and action levels) 4. Heavy metals (4) (FL list and action levels) 5. Microbiological (FL Compliance 1) 6. Water activity and moisture (useable).
Kratom color strains, like red, green, white, and gold, are not distinct plant species but result from specific processing methods after harvest. Drying, blending, and fermenting techniques create these variations. Each color generally correlates with different effects, such as relaxation for red or energy for white.
Kratom can produce effects similar to both opioids and stimulants. Lower kratom doses can enhance energy and alertness. Higher kratom doses can have sedative effects, leading to relaxation and pain relief.
ACS Laboratory continues to push the industry standards for cannabis, hemp, kratom, and mushroom testing. Outside the normal compliance scope, ACS Laboratory offers multiple a la carte lab testing services for all product types. Hemp and cannabis potency testing covers more than 25 cannabinoids, including hemp-based alternative cannabinoids like Delta-8, Delta-10, HHC, and THCO. Shelf life and stability testing determine expiration dates, packaging safety, and proper storage for hemp, cannabis, mushroom, and kratom ingestibles.Early testing for moisture content and water activity shows signs of dangerous bacteria across all product types.A full Plant Health Panel for hemp and cannabis encompasses multiple tests for viruses, mycotoxins, pesticides, fungi, and other microorganisms.Vitamin E Acetate testing ensures all vapes are 100% free of harmful thinning agents, now a required test in certain Hemp states like Florida.Homogeneity testing in edibles confirms consistent potency throughout. Amanita mushroom potency tests quantify active ingredients and ensure Amanita products are free from illicit psilocybin and psilocin.Kratom testing verifies the absence of contaminants like heavy metals, including manganese, pesticides, and residual solvents. If you don’t find what you’re looking for, contact ACS about R&D opportunities and method development.
THCA exhibits neuroprotective effects, meaning it protects the brain. It also possesses potent anti-inflammatory properties, has the potential to slow down the growth of cancer cells, reduce nausea, and may provide relief for seizure disorders.
R&D testing is for internal insights and doesn't need to be reported to regulators. It includes tests on raw materials (like soil or pre-harvest samples) to check potency and contaminants before products are finalized. It can also involve testing new formulations to improve product safety, like ACS Laboratory’s HHC Heavy Metals Bundle or kratom panels. Compliance testing, on the other hand, is often legally required for products sold in regulated markets, such as cannabis, hemp, and psilocybin mushrooms in Colorado and Oregon. It typically includes tests for potency (like ensuring Delta-9 THC is below 0.3%) and contaminants, such as heavy metals, pesticides, solvents, and harmful microbes. For DEA-registered mushrooms, compliance testing may also verify psilocybin and psilocin levels on labels.
CBDV is a homolog of CBD, meaning it shares a similar chemical structure but has distinct differences that lead to varied effects and applications. Both CBDV and CBD are non-psychoactive cannabinoids and have been studied for their potential therapeutic applications, including anti-inflammatory, anti-convulsant, and anti-anxiety properties. However, research on CBDV is far less extensive than that on CBD.
Clinical trials have proven CBD‚ anti-seizure capabilities, leading to the FDA-approved drug Epidiolex. Conversely, CBDV has yet to pass the FDA approval threshold for medicinal applications. Despite its potential, CBDV remains under-researched compared to its more widely studied counterpart, CBD.
High Amanita muscaria doses can result in intense psychoactive effects, such as vivid dreams and hallucinations. Consuming too high a dose for a person’s tolerance level could also cause some adverse effects, such as: DizzinessConfusionTirednessIncreased sensitivity to visual and auditory stimuliNausea and vomitingMuscle twitching or tremorsSweating and salivation
Kratom’s side effects can include nausea, constipation, dizziness, and, in some cases, dependence or withdrawal symptoms. Consumers must ingest kratom responsibly and be aware of these possible effects.
ACS Laboratory’s cannabis testing panels include:Compliance: ACS Laboratory can quantify up to 32 major and minor cannabinoids in cannabis potency testing. Florida rules require the testing of 11 Major Cannabinoids. ACS also screens for contaminants, including pesticides, heavy metals, mycotoxins, residual solvents (for extracts), microbiology, and other foreign materials, and performs tests for moisture content and water activity.R&D and plant health: ACS offers a full Plant Health Panel, testing for plant viroids,as well as shelf life and stability testing.Full Chemical Profiling: ACS completes terpenes testing and measures flavonoid content for a complete profile of a cannabis product’s flavor, aroma, and therapeutic effects.
The 2018 Farm Bill removed hemp from the federal Controlled Substances List, making it legal to sell and ship hemp-based CBD products containing less than 0.3% THC in the US as long as they comply with applicable federal, state, and local laws. This includes the FDA’s FD&C.
ACS Laboratory’s functional mushroom tests include measuring tryptophan and adenosine levels and specific compounds for individual mushroom species, such as cordycepin in Cordyceps, ganoderma in Reishi, and bulletin and lupeol in Chaga. ACS also conducts purity analyses for pesticides, mycotoxins, residual solvents used when making extracts, heavy metals, microbiological compounds, and water activity and moisture.
Cannabichromene acid (CBCA) is the precursor to cannabichromene (CBC) in the cannabis plant. Upon exposure to heat or light, CBCA undergoes decarboxylation, losing a carboxyl group to become CBC. CBCA itself has not been as extensively studied as CBC. However, early research suggests that CBCA has rapid and potent antibacterial properties against Staphylococcus aureus (MRSA), similar to CBC.
CBD (cannabidiol) is the non-psychoactive component found in cannabis and hemp plants. CBD comes in many forms, including distillate, isolate, and crude oil. Many brands formulate CBD into a wide range of finished consumer products, such as tinctures, salves, topicals, vapes, gel caps, beauty products, and even smokable hemp. CBD products must contain less than 0.3% THC by weight to meet compliance standards for legal sales, which makes THC percentage testing critical during CBD lab testing.
CBN is very similar to CBD in its chemical structure and therapeutic profile. Both cannabinoids show anti-inflammatory and analgesic effects, but CBN has unique antibacterial properties and may stimulate appetite. CBD, on the other hand, is more widely researched for anxiety, epilepsy, and neuroprotection, highlighting its broader therapeutic potential. Additionally, CBN primarily forms as THC ages, resulting in very mild psychoactive effects, unlike CBD, which is non-psychoactive.
CBNA is the acidic version of CBN. Hemp and cannabis plants do not directly synthesize CBNA. Instead, it forms when another compound called tetrahydrocannabinolic acid (THCA) breaks down over time. This breakdown happens due to exposure to air (oxygen) or sunlight (UV light), a process known as oxidative degradation.
Very little research has been conducted on CBNA. However, one in-silico docking study found that CBNA contains antibacterial properties similar to CBN. The study explored how CBNA can inhibit a specific enzyme (TrpE) essential for the bacteria that causes tuberculosis. By targeting this enzyme, CBNA, along with CBGA, could help fight TB, especially in cases where the bacteria have become resistant to existing drugs.</p>
White Maeng Da is a kratom variety known for its energizing and mood-enhancing effects. The specific indoor drying process it undergoes preserves high levels of mitragynine, its primary active compound. Fans seek White Maeng Da for its ability to increase focus and alertness.
A COA from ACS Laboratory is a lab report that verifies the kratom product’s test results, including potency and contaminant levels. Accessible online and via QR code, the COA offers consumers peace of mind and transparency. It can be integrated into product packaging and webpages for easy verification.
For compliance: Cannabis is tested for 11 cannabinoid profiles and potency, pesticides, heavy metals, moisture content & water activity, microbiology, mycotoxins, residual solvents (for extracts), filth and foreign materials.
For R+D and plant health: Plant Viroids, polycyclic aromatic hydrocarbons (PAHs), plant growth regulators (PGRs), and glyphosate, as well as shelf life and stability.
For product differentiation, patient/customer education and marketing: terpene profiles and flavonoids.
Kratom, or Mitragyna speciosa, is a tropical tree native to Southeast Asia and part of the coffee family. Its leaves contain alkaloids that produce stimulating or sedative effects, depending on the dosage. Kratom leaves are commonly used in various derivative forms, including powders, capsules, and teas, for their potential effects on pain relief, mood enhancement, and energy.
Mitragynine and 7-hydroxymitragynine are the primary alkaloids in kratom leaves. Mitragynine is the most abundant compound and provides mild pain relief and stimulation. This alkaloid activates opioid receptors but with lower potency than traditional opioids. 7-Hydroxymitragynine, though present in smaller amounts, is significantly more potent. It delivers stronger pain-relieving effects than mitragynine.
Reports indicate mitragynine displays fewer side effects than classical opioid drugs such as morphine. While rare, cases of mitragynine toxicity can occur, in which people experience adverse effects such as seizures, liver damage, and respiratory issues. Because mitragynine inhibits the P450 enzyme, combining mitragynine with other drugs can cause severe reactions.
Mitragynine is a unique chemical found in the leaves of the Mitragyna speciosa plant (also known as kratom), a tree native to Southeast Asia. The compound works by activating opioid receptors, giving it pain-relieving and stimulating properties similar to those of other opioid drugs, such as morphine.
“Fly agaric” is a nickname for the Amanita muscaria mushroom because it is purported to attract and kill flies.
Full-spectrum cannabis products contain whole-plant cannabinoids and other natural compounds, while isolates solely contain one cannabinoid, like THC or CBD, without any others. For example, full-spectrum CBD oils can contain many different cannabinoids, like CBN and CBG, and terpenes, like lilanool and limone, that offer synergistic effects.
The appropriate dosage of Amanita muscaria for beginners depends on several factors, such as the product type and a person’s body weight, metabolism, and tolerance. Most experts suggest that consumers start with a microdose or low dosage, typically less than 400 mg of Amanita muscaria extract, and gradually increase it.
ACS offers a fast turnaround time of three to five business days for all test results.
ACS mushroom testing analyzes various common mushrooms and finished products, including dried mushrooms (commonly called fruit), powders, tinctures, capsules, beverages, and edibles like chocolates, and gummies..
ACS Laboratory offers a comprehensive array of test panels, from potency testing and pesticides to specialized tests for flavonoids and plant health. These tests include: Potency testing (32 cannabinoids)Pesticide testing (105 analytes)Residual solvent testing (42 analytes)Microbiology testing (17 analytes, including petrifilm and listeria)Mycotoxins (6 analytes)Heavy Metals (25 analytes)Terpenes (38 analytes)Flavonoids (16 analytes)Moisture activityWater activityFilth and foreign materialVitamin E acetate (for hemp, cannabis, and CBD vapes)PH LevelTheanine-Caffeine-MelatoninCustom R&D development (inquire)Custom method development (inquire)
ACS Laboratory offers a comprehensive array of test panels from Potency Testing, Heavy Metals and Pesticides, to specialized tests such as Flavonoids and Plant Regulators.
Test Panels: Potency Testing (23 cannabinoids)
Pesticide Testing (67 analytes)
Residual Solvent Testing (11 analytes)
Microbiology Testing (ACS Laboratory has FIVE different Microbiology panels to choose from in order to suit your needs: Microarray, PCR Pathogenic, Total Bacterial Count, Standard Petrifilm and Listeria.)
Mycotoxins (5 analytes)
Heavy Metals (4 analytes)
Terpenes (38 analytes)
Flavonoids (16 analytes)
Micronutrients
Moisture Activity
Water Activity
Plant Regulators
Filth and Foreign Material
Vitamin E Acetate (*ONLY FOR VAPES FOR HEMP PRODUCTS)
Custom R&D Development (Inquire)
Custom Method Development (Inquire)
ACS Laboratory’s magic mushroom testing includes potency testing of psilocybin, psilocin, harmine, harmane, baeocystin, norbaeocystin, norpsilocin, aeruginascin, 4-hydroxy TMT, and 4-hydroxytryptamine. ACS also performs purity analyses for pesticides, mycotoxins, residual solvents used when making extracts, heavy metals, microbiological compounds, and water activity and moisture.
The percentage of 7-hydroxymitragynine (also 7-OH mitragynine or 7-OH) in kratom can vary widely depending on the specific strain and preparation method. Generally, 7-OH mitragynine constitutes a small percentage of kratom’s total alkaloid content, typically around 0.01% to 0.04%. However, 7-OH mitragynine extracts can contain a significantly higher ratio of up to 2.8% 7-OH, with concentrations as high as 500% more 7-OH than the average kratom plant.
ACS screens for 68 different pesticides using liquid and gas chromatography-mass spectrometry. This extensive panel includes common contaminants like abamectin, acephate, bifenthrin, and more, safeguarding consumers from exposure to harmful chemicals.
ACS Laboratory offers the most comprehensive kratom testing panel,, covering more alkaloids and contaminants than standard industry tests, ACS does this by testing for 8 alkaloids and having an extended heavy metals panel to include Manganese.
ACS tests for 21 solvents in kratom, including acetone, methanol, and toluene, acetone, acetonitrile, benzene, butanes, chloroform, ethanol, ethyl acetate, ethyl ether, and heptane.
ACS Laboratory employs cutting-edge techniques for kratom testing like Liquid Chromatography-Mass Spectrometry (LCMS) and Gas Chromatography-Mass Spectrometry (GCMS).
ACS Laboratory can test a wide range of product types for cannabis, hemp, mushroom, and kratom brands. ACS can test virtually any hemp or CBD plant component and finished product on the shelf, including:Raw biomass, plant material, and budsFlower and pre-rollsEdibles (including gummies and chocolate)VapesConcentratesExtractsOilsTincturesNano cannabis emulsionsBeveragesTopicals, skin creams, and transdermal patchesCannabis and hemp inhalersACS Laboratory also works with psilocybin (“magic”) (DEA Licensed clients only), functional, and Amanita mushroom brands for testing:Dried fruit (mushrooms)PowdersCapsulesEdiblesFor kratom testing with ACS, brands can submit:Leaves and plant samplesEdiblesOther kratom-extract derivative products
ACS Laboratory offers a comprehensive kratom testing panel that covers potency, heavy metals, pathogenic microorganisms, pesticides, and residual solvents. Testing kratom ensures quality, safety, and transparency.
Companies that want to conduct cannabis testing before scheduling a pickup for compliance testing, can use ACS Laboratory’s a la carte R&D testing services. Pre-harvest and post-harvest R&D testing helps brands determine whether cannabis and hemp crops meet compliance standards before reporting results to the state.
ACS Laboratory is located just south of Tampa, Florida: ACS Laboratory 721 Cortaro Drive, Sun City Center, FL 33573
If you’d like to obtain cannabis analysis testing before the state performs compliance tests, we encourage clients to use our a la cart R&D testing services.
Different processing methods modify the alkaloid content in kratom, leading to varied colors and effects. Similar to how cannabis undergoes chemical changes when heated, kratom’s effects shift based on factors like drying duration and exposure to light. This variety helps explain each color's distinct energizing, balancing, or relaxing effects.
ACS tests kratom products for manganese due to research that indicates many kratom products contain excessively high levels of this metal, sometimes up to 20 times the safe limit. High manganese intake can lead to toxic effects, including neurological symptoms resembling Parkinson’s disease. Testing protects consumers from potential health risks linked to manganese exposure in kratom products.
The psilocybin in magic mushrooms or psilocybin mushrooms is a Schedule 1 drug in the U.S., while the muscimol and ibotenic acid in Amanita muscaria are generally unregulated.
Pathogenic testing detects harmful microorganisms, such as E. coli and salmonella, which can be present in raw kratom leaves or derivative products. ACS Laboratory’s testing ensures products are safe for consumption by identifying and eliminating these risks.
Muscimol offers a unique opportunity to explore altered states and therapeutic benefits depending on the dose. In psychoactive doses, muscimol can induce dream-like visions. In smaller amounts, it can support sleep, pain, and anxiety conditions.
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